SLE Focus Rheum| RA Focus Rheum| Rheum for Everyone, Episode 12

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Search results for: heparin

Heparin Fails to Prevent Leg, Lung Clots After Arthroscopy, Casting

Gene Emery  |  

NEW YORK (Reuters Health)—Low-molecular-weight heparin failed to prevent symptomatic venous thromboemboli in people receiving knee arthroscopy or a lower leg cast, according to a pair of studies conducted in the Netherlands. The treatment is controversial because there is little clear evidence that heparin wards off clots in such instances. The research team, led by Dr. Raymond…

Case Report: An Uncommon Presenting Complaint of GPA

Adina Greene, BA, Sabrina Dahak, MD, Wesley A. Robertson, MD, Denege Ward-Wright, MD, & Kristen Young, DO, MEd  |  

Granulomatosis with polyangiitis (GPA) is a small vessel vasculitis associated with anti-neutrophil cytoplasmic antibodies (C-ANCA), specifically proteinase 3 (PR3) ANCA. GPA classically presents with multi-organ involvement. The first description of GPA defined a triad of features: 1) systemic necrotizing angiitis, 2) necrotizing inflammation of the respiratory tract and 3) necrotizing glomerulonephritis.1 Few cases of digital…

Infertility 101: What Every Rheumatologist Should Know

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Infertility is a frequently encountered issue in medicine, seen in about 9% of men and about 11% of women of reproductive age in the U.S.1 Many rheumatologists may not be aware of the prevalence of infertility and the implications this issue may have on the care of their patients. Here, Anat Chemerinski, MD, instructor in…

Case Report: A Patient Presents with Digital Ischemia & Gangrene

Nedal Darwish, MD, Mohamed Manaa, MD, Griffin Reyes, MD, & James G. Freeman, MD  |  

Defined by the presence of antiphospholipid antibodies (aPL) in individuals with clinical evidence of thrombosis or pregnancy morbidity, antiphospholipid syndrome (APS) is a systemic autoimmune thrombophilia. Clinical thrombosis, which should be confirmed by objective validated criteria (e.g., imaging studies or histopathology), can occur in the arterial, venous or small vessel vasculature and is not limited…

A Young Disease: A Holistic Approach to the Treatment of Antiphospholipid Syndrome

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Although progress has been made in recent years, rheumatologists still have a lot of questions regarding best management practices for antiphospholipid syndrome (APS). During a session of EULAR 2022, Ricard Cervera, MD, PhD, described a holistic approach.

Challenges in Reproductive Health in Rheumatic Disease

Keri Losavio & Julie Nusbaum, MD  |  

In light of new challenges to individuals’ reproductive rights and the known challenges of clinical management of rheumatic disease patients during pregnancy, we review the current state of reproductive rheumatology and the management of patients with rheumatic disease during pregnancy.

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Case Report: Blunt Smoker Denies Tobacco Use, Delaying Diagnosis

Rachel E. Elam, MD, ScM, Vishal Arora, MD, & Alyce M. Oliver, PhD, MD  |  

Cannabis arteritis mirrors thrombo­angiitis obliterans in its clinical and arteriographic presentation, but its relevant exposure is cannabis rather than tobacco.1 Whether cannabis arteritis is a subset of thromboangiitis obliterans or a unique pathologic entity is debatable. Delta-9-tetrahydrocannabinol, the primary psychoactive component of cannabis, is a peripheral vasoconstrictor.2 This offers mechanistic insight into how cannabis may…