Case report: A 60-year-old Hispanic male with poorly controlled hypertension was sent from the primary care clinic for evaluation of malignant hypertension with a systolic blood pressure above 200 mmHg. His symptoms at the time of presentation included episodic confusion, worsening vision and an unsteady gait. A head computed tomography (CT) scan showed a subacute…
Researchers in the U.K. have discovered that manipulating T cells to exhaustion in a targeted way may lead to new treatments and predictors for various types of autoimmune diseases…
CHICAGO—Scleroderma patients with pulmonary arterial hypertension (PAH) might benefit from more aggressive therapy, an expert in the field said in a session on lung involvement in rheumatic diseases at the American College of Rheumatology’s 2015 State-of-the-Art Clinical Symposium in May. Newer trials—the SERAPHIN trial on macitentan, GRIPHON on selexipag, and AMBITION on an ambrisentan/tadalafil combination—show…
Researchers from California and Texas have identified a new genetic syndrome that is characterized by systemic autoimmune disease of the lung and joints. The syndrome is driven by a genetic variant of a vesicular transport protein and is the first documented association between intracellular transport and autoimmunity. Levi B. Watkin, PhD, postdoctoral fellow at Baylor…
Links between autoimmunity, malignancy prompt rheumatologists to include cancer screening for patients
New drugs, targeted treatments for idiopathic pulmonary fibrosis
A review of data on antinuclear antibodies and tests for rheumatoid arthritis
Differences in its epidemiologic, clinical and immunologic features underscore need for a homogeneous diagnostic and therapeutic approach
A 48-year-old man with diffuse arthralgias and acute respiratory failure is diagnosed with antisynthetase syndrome
Guidance for diagnosing and treating interstitial lung disease complications