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Search results for: recurrent fever syndromes

New Classification Criteria Describe Several Hereditary Fevers

Larry Beresford  |  September 21, 2020

Evidence-based classification criteria for rare, hereditary, autoinflammatory fevers have been developed to aid clinicians in better understanding the differences between these rare conditions.

Filed under:Conditions Tagged with:ClassificationClassification CriteriaFamilial Mediterranean feverfeverheredity

Laurent/Yakou / Science Source

How to Recognize, Diagnose Periodic Fever Syndromes in Adults

Rick Brasington, MD  |  December 18, 2017

A number of autoinflammatory syndromes that result from genetic mutations have been described recently. The vast majority occur in children. However, three periodic fever syndromes are important for rheumatologists who treat adults to know about. The goal of this review is to provide a concise description of each condition, and to help the clinician understand…

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:adult Still's DiseasearthralgiasArthritisASDautoinflammatoryClinicalDiagnosisFamilial Mediterranean feverfevergenetic mutationoutcomepatient carePediatricreceptor-associated periodic syndromerheumatologistrheumatologyTRAPSTreatment

Cryopyrin-Associated Periodic Syndromes: Difficult to Recognize, Diagnose, Treat

Philip J. Hashkes, MD, MSc, & Ronald M. Laxer, MDCM, FRCPC  |  October 1, 2014

Two case studies demonstrate the difficulty, delay in recognizing this rare autoinflammatory disease

Filed under:Career DevelopmentConditionsEducation & TrainingOther Rheumatic ConditionsProfessional TopicsResearch Rheum Tagged with:autoinflammatoryCAPSClinicalDiagnosispatient careResearchrheumatologistSteroidsTreatment

Inflammatory Origin of Fever Is Key to Diagnosis

Simon M. Helfgott, MD  |  September 1, 2014

Fever in rheumatology patients may present evidence of an inflammatory process

Filed under:ConditionsGout and Crystalline ArthritisOpinionOther Rheumatic ConditionsRheuminationsSpeak Out RheumSystemic Lupus Erythematosus Tagged with:braincrystal arthritisfeverGoutHelfgottimagingInfectioninflammatorymicrobepatient carerheumatologistSarcoidosisSystemic lupus erythematosus

Decoding Autoinflammatory Syndromes

Kathy Holliman  |  January 1, 2010

Understanding the genetic basis of errors of the immune system may provide new opportunities for therapy

Filed under:ConditionsOther Rheumatic Conditions Tagged with:ACR/ARHP Annual MeetingautoinflammatorygeneticsInterleukinsystemic autoinflammatory diseasestumor necrosis factor

Management Updates for a Spectrum of Systemic Autoinflammatory Diseases

Ruth Jessen Hickman, MD  |  January 19, 2024

SAN DIEGO—As part of a panel on systemic autoinflammatory diseases (SAIDs) at a Nov. 15 scientific session of ACR Convergence 2023, Sivia Lapidus, MD, shared context and insights on the therapeutic management of patients with these conditions. The Spectrum of SAIDs SAIDs encompass a broad swath of individually rare disorders driven by innate immune responses…

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2023CAPSCOVID-19Familial Mediterranean feverPFAPATRAPS

Mattew - Bilder und mehr / shutterstock.com

Yao Syndrome: A Case Report & Clinical Review

Peter Gorevic, MD, & Qingping Yao, MD, PhD  |  November 12, 2020

Case Presentation History of present illness A 66-year-old white woman presented with unexplained, recurrent episodes of high fever, abdominal pain, rash and arthralgias occurring over the previous three years. During typical episodes, the patient experienced flu-like symptoms, followed by fever, abdominal pain and non-bloody diarrhea without tenesmus. Her temperatures were 101–103ºF, with chills lasting up…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:case reportNOD2-associated auto­inflammatory diseaseYao Syndrome

Curbside Consults: Experts Weigh in on Complex Rheumatic Conditions

Thomas R. Collins  |  February 14, 2024

In this ACR Convergence 2023 session, experts offered guidance on a selection of diagnostic & treatment challenges rheumatologists may encounter.

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic ConditionsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2023Behçet’s diseasenerve entrapmentoral ulcer

Case Report: A Long, Arduous Evaluation Capped by Genetic Testing

Saud Abaalkhail, MD, Muhammad Umair Javaid, DO, & Amarie Negron Rodriguez, MD  |  February 14, 2023

Systemic autoinflammatory diseases (SAIDs) are rare syndromes characterized by alterations in innate immunity that result in a variety of clinical manifestations that are usually associated with recurrent fevers.1 Thanks to advances in genetic sequencing over the past few years, monogenic causes for some of these autoinflammatory diseases, such as Yao syndrome, have been discovered.2 Previously…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:canakinumabcase reportNOD2-associated auto­inflammatory diseaseYao Syndrome

Highlights from the ACR Review Course 2022

Samantha C. Shapiro, MD  |  December 6, 2022

PHILADELPHIA—At ACR Convergence 2022, the much-anticipated ACR Review Course featured talks from eight experts. Topics reflected the heterogeneity of our field and included Sjögren’s disease, spondyloarthritis (SpA), osteoarthritis (OA), paraneoplastic rheumatic syndromes, metabolic bone disease, statin myopathy, Raynaud’s phenomenon and autoinflammatory syndrome. Here, I share highlights from this comprehensive, six-hour session. Sjögren’s Disease Sara S….

Filed under:ACR ConvergenceConditionsMeeting ReportsOsteoarthritis and Bone DisordersOther Rheumatic ConditionsSjögren’s Disease Tagged with:ACR Convergence 2022ACR Convergence 2022 – ASautoinflammatory diseasemetabolic bone diseaseosteoarthritis (OA)paraneoplastic rheumatic syndromesRaynaud’s phenomenonSjogren'sspondyloarthritis (SpA)statin myopathy

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