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Search results for: Biologics

Certolizumab Pegol Usage Compatible with Breastfeeding

Michele B. Kaufman, PharmD, BCGP  |  December 20, 2016

In a small-scale study, researchers found that no, or minimal amounts of, certolizumab pegol transfers from mothers taking the drug to nursing infants…

Filed under:Drug Updates Tagged with:breast milkbreastfeedingCertolizumab Pegolinfantspregnancy

The Future of Pediatric Rheumatology Grounded in Evolution of Childhood Arthritis and Rheumatology Research Alliance

Yukiko Kimura, MD, & Laura E. Schanberg, MD  |  December 15, 2016

Pediatric rheumatology was formally recognized as a specialty in 1991 by the American Board of Pediatrics. Prior to this time, children with rheumatic diseases were treated by a hodgepodge of providers. In addition to providers who had training as pediatric rheumatologists, general pediatricians, adult rheumatologists, allergist-immunologists, orthopedists, pediatric infectious disease specialists and others treated children…

Filed under:ConditionsPediatric ConditionsProfessional TopicsProfiles Tagged with:CARRAChildhood Arthritis & Rheumatology Research AlliancefutureHistorypatient carePediatricProfilerheumatology

Infection Greater Worry Than Flare: Collaborative Guideline Offers Guidance to Prevent Joint Replacement Complications & Failure

Susan Bernstein  |  December 14, 2016

WASHINGTON, D.C.—Total joint arthroplasty is one of the most common surgical procedures performed on adults with end-stage arthritis. One recent estimate showed that 2.5 million individuals in the U.S. are living with a total hip replacement and 4.7 million are living with knee replacements. For their patients with inflammatory arthritis, rheumatologists and orthopedic surgeons must…

Filed under:Clinical Criteria/GuidelinesMeeting ReportsProfessional Topics Tagged with:2016 ACR/ARHP Annual Meetingdraft guidelineguideline projectjoint implant failurePerioperative Management of Anti-Rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplastyperioperative periodpostoperative infection

The 2016 ACR Award Winners Discuss Their Contributions to Rheumatology Research, Education, Patient Care

Richard Quinn  |  December 13, 2016

At the 2016 ACR/ARHP Annual Meeting in Washington, D.C., in November, the ACR and the ARHP honored a group of distinguished individuals who have made significant contributions to rheumatology research, education and patient care. In the November 2016 issue, we reported on the ARHP’s awards. This month, we speak with the ACR winners. Presidential Gold…

Filed under:Awards Tagged with:AC&RACR/ARHPAmerican College of Rheumatology (ACR)Awardsrheumatologywinner

U.S. Supreme Court Declines to Hear Biologic Drug Patent Fight

Brendan Pierson  |  December 12, 2016

WASHINGTON (Reuters)—The U.S. Supreme Court on Monday declined to hear a case over whether companies that make copycat versions of biologic drugs must wait six months after winning federal approval before bringing them to the market. The justices opted not to take up Apotex Inc.’s appeal of a July federal appeals court ruling that could…

Filed under:Biologics/DMARDsDrug Updates Tagged with:Amgenbiologic drugsBiosimilarslawsuitLegal

Obesity & Rheumatic Disease

Richard Quinn  |  December 9, 2016

“Obesity is an inflammatory state, so it is in the landscape of the rheumatologist,” says Christopher Ritchlin, MD, MPH. And the more attention rheumatologists pay to obesity, the better…

Filed under:Conditions Tagged with:DietinflammationObesitypreventiveRheumatic Disease

Health Policy Resolutions from the AMA House of Delegates 2016 Interim Meeting

Kelly Tyrrell  |  November 30, 2016

This year’s interim meeting of the American Medical Association (AMA) House of Delegates (HOD) took place Nov. 12–15, just days after the national election that, in 2017, will usher in a GOP-led Congress and presidential administration. “It was a highly interesting meeting,” says Gary Bryant, MD, FACP, associate professor of medicine and rheumatology at the University…

Filed under:Meeting ReportsProfessional Topics Tagged with:AMAAMA House of Delegates (HOD)American Medical Association (AMA)Healthcare ReformHouse of Delegates interim meeting

FDA Update on Rituximab & Etanercept; Plus New ACP Gout Guideline

Michele B. Kaufman, PharmD, BCGP  |  November 30, 2016

The FDA is considering an application for subcutaneous rituximab and has approved an application for etanercept to treat pediatric patients with plaque psoriasis…

Filed under:Biologics/DMARDsConditionsDrug UpdatesGout and Crystalline ArthritisPediatric Conditions Tagged with:American College of PhysiciansetanerceptFDAFood and Drug AdministrationGoutguidelinePediatricplaque psoriasisrituximab

Reinitiating TNF Blockers after Tuberculosis Treatment

Michele B. Kaufman, PharmD, BCGP  |  November 23, 2016

A retrospective study showed that patients who have rheumatic disease and develop tuberculosis may be able to resume anti-TNF therapy and other biologic agents…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabAnti-TNFetanerceptInfectioninfliximabrituximabTuberculosistumor necrosis factor inhibitorTumor Necrosis Factor–Alpha Inhibitor

Transfer of Certolizumab in Breast Milk Not a Concern

Reuters Staff  |  November 22, 2016

NEW YORK (Reuters Health)—There is minimal to no transfer of the tumor necrosis factor (TNF) inhibitor certolizumab (Cimzia) from plasma to breast milk, according to a new study. “These findings are reassuring” and imply that continuing certolizumab treatment is compatible with breastfeeding, Dr. Megan Clowse of Duke University School of Medicine in Durham, North Carolina,…

Filed under:Drug Updates Tagged with:breast milkCertolizumab PegolTNFTNF inhibitor

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