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Search results for: methotrexate

The Role of ANA Positivity in Patients with RA

Susan Bernstein  |  September 28, 2021

Recent research suggests patients with RA and a positive test for anti-nuclear antibody (ANA) may not have a different disease course than patients with RA who test negative for ANA. However, these patients may experience different treatment courses.

Filed under:ConditionsRheumatoid Arthritis Tagged with:ANAANA-positive RAanti-nuclear antibodiesRheumatoid Arthritis (RA)

Experts Share Insights & Advice on Reproductive Health for Patients with Rheumatic Disease

Kelly Tyrrell  |  September 24, 2021

Contraception, disease control, family planning and managing life with an infant—five experts addressed these concerns and more for patients with rheumatic disease during a special online webinar.

Filed under:Conditions Tagged with:contraceptivefamily planningpatient carepregnancyreproductive healthRheumatic Disease Awareness Month (RDAM)

Vasculitis Guidelines in Focus, Part 4: Polyarteritis Nodosa

Michael Putman, MD  |  September 22, 2021

Jason Springer, MD, MS, served as one of the lead authors of the ACR/VF guidelines for polyarteritis nodosa (PAN), and talks about the recommendations specific to PAN here.

Filed under:Clinical Criteria/GuidelinesConditionsVasculitis Tagged with:Guidelinespolyarteritis nodosaVasculitisVasculitis Foundation

Vasculitis Guidelines in Focus, Part 3: EGPA

Michael Putman, MD  |  September 14, 2021

In this third article in the series, we talk with Philip Seo, MD, MHS, about eosinophilic granulomatosis with polyangiitis (EGPA).

Filed under:Clinical Criteria/GuidelinesConditionsVasculitis Tagged with:AAV FocusRheumEGPAeosinophilic granulomatosis with polyangiitis (EGPA)guidelineVasculitis

Case Report: Sarcoidosis in Patient with History of IgG4-Related Disease

Veronica Matto, DO, Rajshri Shah, MD, Jie Ouyang, MD, PhD, Cory Perugino, DO, & Joseph J. LaConti, MD, PhD  |  September 14, 2021

Sarcoidosis and IgG4-related disease (IgG4-RD) are both immune-mediated, often multi-organ, diseases of uncertain etiology capable of presenting with diverse clinical manifestations. Many clinical features are common to both conditions, including hypergammaglobulinemia, the ability to form inflammatory masses and involvement of the lymph nodes, lacrimal glands, salivary glands, meninges and lungs. Although imaging modalities, such as…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:IgG4 related diseaseSarcoidosis

Vasculitis Guidelines in Focus, Part 2: ANCA-Associated Vasculitis

Michael Putman, MD  |  September 9, 2021

Sharon Chung, MD, MAS, discusses specific recommendations for the treatment and management of ANCA-associated vasculitis from the latest ACR Guideline.

Filed under:Clinical Criteria/GuidelinesConditionsVasculitis Tagged with:AAV FocusRheumANCA-Associated VasculitisguidelineVasculitisVasculitis Foundation

EU Approves Tofacitinib Citrate for 2 Pediatric Conditions

Michele B. Kaufman, PharmD, BCGP  |  September 8, 2021

The European Commission approved tofacitinib citrate to treat two pediatric conditions, as well as a prolonged-release version of the medication designed to treat adults with active PsA.

Filed under:ConditionsDrug UpdatesPediatric ConditionsPsoriatic Arthritis Tagged with:drug approvalsEuropeEuropean Unionjuvenile idiopathic arthritis (JIA)juvenile PsAPediatricPediatric RheumatologyPsAPsoriatic Arthritistofacitinib citrate

FDA Requires New Boxed Warnings on JAK Inhibitors, Places Restrictions on Use

Keri Losavio  |  September 1, 2021

On Sept. 1, the U.S. Food & Drug Administration (FDA) announced that it is requiring revisions to the Boxed Warning for the Janus kinase (JAK) inhibitors Xeljanz/Xeljanz XR (tofacitinib), Olumiant (baricitinib) and Rinvoq (upadacitinib) to include information about the risks of serious heart-related events, cancer, blood clots and death.1 Recommendations for healthcare professionals will include…

Filed under:Drug Updates Tagged with:baricitinibJAK inhibitorsjakinibsTofacitinibupadacitinib

COVID-19 Vaccine Efficacy & Safety Discussed at Town Hall

Ruth Jessen Hickman, MD  |  August 20, 2021

At a recent ACR town hall, panelists described immune responses and side effects of COVID-19 vaccination in patients with rheumatic disease, along with ways to leverage monoclonal antibody treatments, especially in light of virus variants.

Filed under:American College of Rheumatology Tagged with:COVID-19immunosuppressionvaccination

Healthcare Extenders Can Reduce Physician Burden & Improve Patient Access & Care

Kimberly Steinbarger, PT, MHS, DHSc, & Saba Mohiuddin, PharmD, BCACP  |  August 11, 2021

In the early 1900s, the treatment for rheumatic and musculoskeletal disease (RMD) was primarily targeted at symptomatic relief and included analgesics, physical therapy, splinting and bed rest. With the discovery of methotrexate and its impact on rheumatoid arthritis (RA) management, a much-needed evolution of medications targeting disease activity began. Over the past 30 years, several…

Filed under:Interprofessional PerspectiveWorkforce Tagged with:Advanced Practice CliniciansAssociation of Rheumatology Professionals (ARP)dietitiannurse practitioneroccupational therapistspharmacistphysical therapistphysician assistantssocial worker

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