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Search results for: musculoskeletal disease

Case Report: Sweet Syndrome as an Initial Presentation of Crohn’s Disease

Ryan Guerrettaz, MD, Angelo Ciliberti, MD, Rochella Ostrowski, MD, Elise Wolff, DO, Nadia Qureshi, MD, & Ramzan Shahid, MD  |  July 13, 2022

Acute febrile neutrophilic dermatosis, or Sweet syndrome, is an inflammatory disease that classically presents with fever, leukocytosis and tender, erythematous plaques characterized by neutrophilic infiltrates on biopsy. Sweet syndrome has been reported in association with several autoimmune diseases, including inflammatory bowel disease, systemic lupus erythematous, rheumatoid arthritis and sarcoidosis.1 Here, we discuss a case of…

Filed under:Conditions Tagged with:case reportCrohn's diseaseFellowsFellows ForumSweet's syndrome

Challenges in Reproductive Health in Rheumatic Disease

Keri Losavio & Julie Nusbaum, MD  |  July 11, 2022

In light of new challenges to individuals’ reproductive rights and the known challenges of clinical management of rheumatic disease patients during pregnancy, we review the current state of reproductive rheumatology and the management of patients with rheumatic disease during pregnancy.

Filed under:ConditionsDrug UpdatesMeeting ReportsRheumatoid ArthritisSystemic Lupus Erythematosus Tagged with:Access to Reproductive Health Care Task Forcedisease managementLegalMethotrexatepregnancyreproductive healthReproductive Health in Rheumatic Disease Symposium

Scleroderma & ILD: Practical Tips on the Diagnosis & Management of Systemic Sclerosis-Associated Interstitial Lung Disease

Samantha C. Shapiro, MD  |  June 15, 2022

No one-size-fits-all approach exists for the care and treatment of patients with systemic sclerosis (SSc) and SSc with pulmonary involvement. Here, experts discuss some best clinical practices for these patients.

Filed under:ConditionsSystemic Sclerosis Tagged with:ILDinterstitial lung disease (ILD)lungsnintedanibSclerodermaSSc-ILDsystemic sclerosis (SSc)tocilizumab

Axial Disease in Psoriatic Arthritis

Philip Helliwell, DM, PhD, FRCP  |  May 6, 2022

When Moll and Wright first described the spondyloarthritides in the early 1970s, the archetype of the group was ankylosing spondylitis (AS).1 The shared clinical features of the spondyloarthritides were sacroiliitis; asymmetric large joint peripheral arthritis; psoriasis or psoriaform skin lesions, including keratoderma blennorrhagica; uveitis; and bowel inflammation. Moll and Wright described five clinical subgroups of…

Filed under:Axial SpondyloarthritisConditionsPsoriatic Arthritis Tagged with:Ankylosing SpondylitisAxial Psoriatic Arthritis (axPsA)Psoriatic Arthritis

Outcomes in Patients with Rheumatic Diseases & COVID-19

Arthritis & Rheumatology  |  April 26, 2022

Background & objectives: Patients with rheumatic and musculoskeletal diseases (RMDs) may be at an increased risk of SARS-CO-V2 infection as a result of underlying disease, associated comorbidities and use of potentially immunosuppressive treatments. Further, concern exists regarding whether individuals with rheumatic diseases potentially experience more severe COVID-19 and poorer outcomes. This study was undertaken to…

Filed under:ConditionsResearch Rheum Tagged with:Arthritis & RheumatologycomorbiditiesCOVID-19musculoskeletal diseaseResearchRheumatic Disease

COVID-19 Vaccination in Patients with Rheumatic Disease

Arthritis & Rheumatology  |  January 5, 2022

In January A&R, Simon et al. report a study to assess humoral and cellular immune responses after infection with, or vaccination against, SARS-CoV-2 in patients with B cell depletion and controls who are B cell competent, finding that B cell depletion completely blocks humoral but not T cell SARS-CoV-2 vaccination response. In the same issue, Connolly et al. evaluated disease flare and post-vaccination reactions in patients with rheumatic and musculoskeletal diseases following messenger RNA (mRNA) vaccination.

Filed under:ConditionsResearch Rheum Tagged with:Arthritis & RheumatologyCOVID-19flaremusculoskeletal diseaseResearchRheumatic DiseaseSARS-CoV-2vaccination

Gout, Imaging & Cardiovascular Disease: 2 Experts Discuss Challenging Patients & Advanced Imaging

Samantha C. Shapiro, MD  |  November 23, 2021

Experts compare using ultrasound and dual-energy computed tomography (DECT) scan when diagnosing likely gout patients, and discuss the latest insights into the intersection between gout and cardiovascular disease.

Filed under:ACR ConvergenceConditionsGout and Crystalline ArthritisMeeting Reports Tagged with:ACR Convergence – GoutACR Convergence 2021Goutimaging

Regressed germinal center with follicular dendritic cell prominence (star), onion-skinning (blue arrowhead) and increased vascularity (orange arrows) are seen.

Case Report: Is It Castleman Disease, or Castleman-Like?

Philip Chu, MD, RhMSUS, Mithu Maheswaranathan, MD, Jadee L. Neff, MD, PhD, & Rebecca E. Sadun, MD, PhD  |  October 13, 2021

The difference between Castle­man disease and Castleman-like disease may be subtle, but it comes with significant ramifications. Case Presentation This case involves a pregnant 19-year-old woman who presents over multiple hospitalizations with concerns for systemic lupus erythematosus and macrophage activation syndrome. At 36 weeks’ gestation, the patient’s weight had dropped from 215 lbs. to 170…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:case reportCastleman's disease

Experts Share Insights & Advice on Reproductive Health for Patients with Rheumatic Disease

Kelly Tyrrell  |  September 24, 2021

Contraception, disease control, family planning and managing life with an infant—five experts addressed these concerns and more for patients with rheumatic disease during a special online webinar.

Filed under:Conditions Tagged with:contraceptivefamily planningpatient carepregnancyreproductive healthRheumatic Disease Awareness Month (RDAM)

Case Report: Saddle Nose Deformity in IgG4-Related Disease

Alyxandra Soloway, MD, & Stephen Soloway, MD, FACP, FACR  |  June 14, 2021

Immunoglobulin G4-related disease (IgG4-related disease) is relatively rare, although with greater recognition it is becoming more frequently diagnosed. Some of the more common presentations of the disease include aortitis, cholangitis, autoimmune pancreatitis, sclerosing sialadenitis, orbital disease with proptosis and subacute mass development in the affected organ.1 It has protean manifestations and is diagnosed by classic…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:case reportIgG4 related diseasesaddle nose deformity

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