The etiology of psoriatic arthritis (PsA) is poorly understood but current evidence supports an interaction between genetic and environmental factors that coalesce to promote local tissue inflammation.1-3 The pivotal cytokines that underlie the local inflammatory response in a wide range of tissues are interleukin (IL) 23, IL-17 and tumor necrosis factor (TNF).4 The central contribution…
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Looking to Psoriatic Arthritis History to Disrupt Current Thinking
As the cloud moved away from the tent, Miriam’s skin suddenly became diseased, as white as snow. When Aaron turned toward her, he saw that she was diseased. —Numbers 12:10 For 29 years he [Fray Pedro de Urraca] was afflicted by … pain, suffering it at once in all the joints of his body, with…
Spring 2022’s Awards, Appointments & Announcements in Rheumatology
Martin Kriegel, MD, PhD, Receives 2021 Lupus Insight Award “I have always found the conundrum of autoimmunity interesting. It’s fascinating to find out why the immune system attacks the body, how it can distinguish self from non-self,” says Martin Kriegel, MD, PhD, head of the Department of Translational Rheumatology & Immunology, Institute of Musculoskeletal Medicine,…
The 2021 ACR Awards of Distinction & Distinguished Fellows
During ACR Convergence 2021 in early November, the ACR honored a group of individuals who have made significant contributions to rheumatology research, education and patient care, announcing the recipients of the ACR’s 2021 Awards of Distinction, as well as the group of Distinguished Fellows. recognized for their contributions. Three pediatric rheumatologists and one pediatric fellow…
Advances in Rheumatology & Challenges that Remain Spotlighted in ACR Convergence 2021 Closing Session
The diverse topics, research & perspectives from this year’s ACR Convergence bring new insights for rheumatologists & all who care for their patients, according to speakers at the meeting’s Closing Session.
Top 12: Research in Systemic Lupus Erythematosus at a Glance
Dr. Pisetsky’s picks for the top research in lupus presented at ACR Convergence 2021.
Food, Diet, Nutrition & Rheumatic Diseases—Are They Really Related?
“‘I didn’t say there was nothing better,’ the King replied. ‘I said there was nothing like it.’” —Lewis Carroll, Through the Looking Glass “Why did I get this? Was it because of my diet? What should I eat now? What diet should I follow? Are there any natural treatments I can take instead of medications?”…
Highlights, Pearls & News from ACR Convergence 2020
ACR CONVERGENCE 2020—In a year like no other, the 2020 virtual ACR Convergence was a meeting like no other. Nonetheless, the meeting introduced a healthy mix of clinical insights and take-home pearls, according to panelists in the meeting’s closing session, Bright Future: Discovery & Growth. In this session, panelists discussed some of the biggest news…
Cytokine Targets & Treatment Developments for Psoriatic Arthritis & Spondyloarthritis
ACR CONVERGENCE 2020—In recent years, a pathophysiological role for the interleukin (IL) 17/IL-23 axis in the development of psoriasis, enthesitis and inflammatory arthritis has been investigated in both rodent and human models. Clinical trials have demonstrated differential benefits for skin disease and joint disease in patients with psoriatic arthritis, axial spondyloarthritis (axSpA) and ankylosing spondylitis…
Diet, Microbes & Inflammation: Unique Microbial Genetic Strains in Inflammatory Disease, Plus a Possible Arthritis Diet
Experts at ACR Convergence 2020 addressed how diet & the body’s microbiome affect chronic diseases.
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