The first biosmilar products have been approved in the U.S. and Canada, following Europe’s early lead. Canada approved its first biosimilar monoclonal antibody (mAb) therapy, known as Inflectra (infliximab), on March 30, 2015.1 In Canada, biosimilars are being called subsequent entry biologic (SEB) agents. Inflectra is approved for treating patients with rheumatoid arthritis (RA), ankylosing…
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Dermatology Symptoms Point to Connective Tissue Disorder
The Case A 68-year-old woman with a past medical history of Charcot-Marie-Tooth presents with thickening of the skin on her trunk and extremities, which she has had for the past seven months (see Figures 1 and 2). Her symptoms first began with swelling of her bilateral upper and lower extremities. She is now having difficulty…
Imaging in Ankylosing Spondylitis
MRI inflammation, fat and new bone formation in the sacroiliac joints, spine in patients with AS
Biosimilar for Infliximab Launched in Europe
Plus, updates on arhalofenate, ALO-02, and other rheumatology drug news, safety information
2014 ACR/ARHP Annual Meeting: Methotrexate Use in Patients with RA
Review of clinical research on methotrexate therapy, effect on patients’ functionality, tolerability, adverse events
2014 ACR/ARHP Annual Meeting: Super Proteins Eyed in Therapies for Rheumatic Diseases
Immunoglobulin superfamily of proteins, CTLA-4 and PD-1, may generate treatments for RA, SLE
2014 ACR/ARHP Annual Meeting: Rheumatologic Research Uncovers Clues to Therapies
Studies explore role of STING pathway in bone remodeling, denosumab to reduce fracture risk, autotaxin’s role in fibrosis, SSc
New Therapeutics for Osteoarthritis May Be in Sight
Overview of OA pathogenesis, recent discoveries suggest new treatment strategies are possible
Infliximab, Tocilizumab Can Help in Large Vessel Vasculitis
Case studies show some patients with LVV can achieve remission after treatment with biological agents
Certolizumab Pegol Drug Studies Find No New Safety Issues
Plus, updates on clazakizumab, hydrocodone bitartrate extended-release capsules and other rheumatology drug news, safety information
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