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Search results for: Tofacitinib

RISE Lifts Research: The 2018 Annual Meeting Features 6 New Studies Based on RISE Data

Susan Bernstein  |  October 3, 2018

Data from the ACR’s Rheumatology Informatics System for Effectiveness (RISE) were used by rheumatology researchers in a crop of new studies that will be presented at the 2018 ACR/ARHP Annual Meeting, Oct. 19–24 in Chicago. Six abstracts, including four oral and two poster presentations, were accepted for this year’s meeting. They explore topics ranging from…

Filed under:American College of RheumatologyEducation & TrainingProfessional Topics Tagged with:2018 ACR/ARHP Annual MeetingRheumatology Informatics System for Effectiveness (RISE) clinical data registryRISE data

Case Report: A Psoriatic Arthritis Patient with Dactylitis & Enthesitis

Samantha C. Shapiro, MD; Jemima Albayda, MD; & Ana-Maria Orbai, MD, MHS  |  September 20, 2018

A 36-year-old woman presented at the Johns Hopkins Arthritis Center for a second opinion regarding a diagnosis of psoriatic arthritis (PsA). One year prior to our evaluation, she had developed pain and stiffness in her hands, feet, knees, ankles, elbows and shoulders. She had mild plaque psoriasis of the scalp and base of the neck,…

Filed under:ConditionsOther Rheumatic ConditionsPsoriatic Arthritis Tagged with:DactylitisEnthesitisPsAPsoriatic Arthritis

4 Rheumatoid Arthritis Therapy Principles, & New Drug Info

Thomas R. Collins  |  July 19, 2018

CHICAGO—Amid what she called a “dizzying array of choices” for rheumatoid arthritis (RA)—from anti-TNF and anti-IL6-receptor therapies to B cell depletion to new biosimilar options—disease treatment should still revolve around several basic concepts, an expert said at the ACR State-of-the-Art Clinical Symposium in April. Joan Bathon, MD, chief of rheumatology at Columbia University in New…

Filed under:ConditionsRheumatoid Arthritis Tagged with:2018 State of the Art Clinical SymposiumBiosimilarsDisease-modifying antirheumatic drugs (DMARDs)ILDInterstitial Lung Disease

Study Results for 9 New Psoriatic Arthritis Drugs

Thomas R. Collins  |  June 21, 2018

CHICAGO—As Eric Ruderman, MD, professor of medicine in rheumatology at Northwestern University Feinberg School of Medicine in Chicago, began his talk on psoriatic arthritis treatment at the ACR State-of-the-Art Clinical Symposium in April, he marveled a bit at how much there was to cover. Drugs gaining prominence in the treatment of rheumatoid arthritis and dermatological…

Filed under:ConditionsDrug UpdatesOther Rheumatic Conditions Tagged with:abataceptapremilastBimekizumabguselkumabixekizumabPsoriatic ArthritisrisankizumabsecukinumabTofacitinibustekinumab

FDA Clears Pfizer’s Xeljanz for Inflammatory Bowel Disease

Reuters Staff  |  May 31, 2018

(Reuters)—The U.S. Food and Drug Administration said on Wednesday that it had approved Pfizer Inc’s drug, Xeljanz, to treat adults with moderate-to-severe active ulcerative colitis. The effectiveness of Xeljanz (tofacitinib) in treating ulcerative colitis was shown in three controlled clinical trials, including two trials that showed the drug caused disease remission in about 17-18 percent…

Filed under:Drug Updates Tagged with:Pfizer Inc.TofacitinibU.S. Food and Drug Administrationulcerative colitisXeljanz

DMARDs & Biologics Info for Rheumatology Nurses

Larry Beresford  |  March 17, 2018

SAN DIEGO—In a presentation on what rheumatology nurses should know in their daily practice about disease-modifying anti-rheumatic drugs (DMARDs) at the 2017 ACR/ARHP Annual Meeting Nov. 3–8, Jessica Farrell, PharmD, highlighted the importance of educating and counseling patients about the range of treatments and applications for rheumatologic conditions. Dr. Farrell, a clinical pharmacist at the…

Filed under:Biologics/DMARDsMeeting Reports Tagged with:ACR/ARHP Annual MeetingBiologicsDisease-modifying antirheumatic drugs (DMARDs)

Rheumatoid Arthritis Research Advances

Larry Beresford  |  February 18, 2018

SAN DIEGO—In a roundup of current research in rheumatoid arthritis (RA) presented at the 2017 ACR/ARHP Annual Meeting Nov. 3–8, Mark C. Genovese, MD, professor of medicine in the Division of Immunology and Rheumatology at Stanford University, Palo Alto, Calif., urged his audience to reflect on the impact therapy advances have made on RA. “In…

Filed under:Meeting ReportsRheumatoid Arthritis Tagged with:ACR/ARHP Annual Meetingcombination therapyimagingInfection

Long-Term Benefits, Risks of Biologic Disease-Modifying Anti-Rheumatic Drugs in Patients with RA

Nan Yang, PharmD, & Kurt Oelke, MD, on behalf of the ARHP Practice Committee  |  December 19, 2017

Two decades have passed since the first biologic disease-modifying anti-rheumatic drug (bDMARD) was approved. Studies on the long-term use of biologics in different disease states, such as for cardiovascular disease (CVD) and malignancy, as well as for knee/hip replacement, reveal some encouraging news. In clinical trials, bDMARDs have been shown to increase the risk of…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Association of Rheumatology Professionals (ARP)bDMARDbenefitsbiologic disease-modifying antirheumatic drugsCardiovascular diseaseClinicalhipkneeoutcomepatient carereplacementResearchRheumatoid arthritisrheumatologistrheumatologyriskstudytherapy

Kateryna Kon / Shutterstock.com

How to Manage, Treat Anemia of Inflammation in Patients with Rheumatic Disease

Ruth Jessen Hickman, MD  |  December 17, 2017

Anemia is common in patients with systemic rheumatic disease, yet it may not get the attention it deserves. Anemia can result from chronic inflammation, treatment side effects or other disease factors, or it may signal an unrelated condition. Although diagnosis and treatment of anemia are sometimes challenging, clinicians must do their utmost to rigorously investigate…

Filed under:Conditions Tagged with:anemiaCauseClinicalDiagnosisinflammationkidneymacrocytic anemiaManagementoutcomepathophysiologypatient careRheumatic Diseaserheumatologistrheumatologysystemic inflammatory syndromeTestTreatmentvitamin deficiency

Collaborative Guideline Addresses the Perioperative Use of Antirheumatic Drug Therapy

Arthritis & Rheumatology  |  July 25, 2017

A new guideline developed by the ACR and the American Association of Hip and Knee Surgeons addresses the perioperative use of antirheumatic drug therapy. Specifically, it provides recommendations on the use of traditional disease-modifying antirheumatic drugs, biologic agents, tofacitinib and glucocorticoids in adults with RA; SpA, including ankylosing spondylitis and psoriatic arthritis; JIA; or SLE undergoing elective THA or TKA. The guideline provides recommendations regarding when to continue, when to withhold and when to restart these medications, and the optimal perioperative dosing of glucocorticoids…

Filed under:ConditionsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:Arthritis & RheumatologyClinical GuidelineshipkneeResearchsurgerytotal hip arthroplastytotal knee arthroplasty

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