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Search results for: Tofacitinib

FDA Advisory Committee Votes in Favor of Romosozumab Approval

Michele B. Kaufman, PharmD, BCGP  |  January 30, 2019

An FDA advisory committee voted 18-1 in favor of approving romosozumab to treat postmenopausal women with osteoporosis.

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:boneFDAOsteoporosisromosozumabU.S. Food and Drug Administration (FDA)

Moderate Liver Enzyme Elevation Found in Patients With & Without Hepatic Steatosis

Carina Stanton  |  January 2, 2019

Limited data are available on liver enzyme elevation in patients with RA, PsA and psoriasis being treated with tofacitinib and methotrexate. But early study findings are shedding light on the nature and risks of liver enzyme levels in these patients…

Filed under:Conditions Tagged with:fatty liver diseasehepatic steatosisliverliver enzyme levelsTofacitinib

New Guideline for the Treatment of Psoriatic Arthritis

Arthritis & Rheumatology  |  December 18, 2018

ACR guidelines include recommendations for the management of patients with particular conditions or diseases. Guidelines are developed using a systematic process and are based on available evidence and the clinical experience and expertise of rheumatologists and other interested stakeholders. In the January issue of Arthritis & Rheumatology, Arthritis Care & Research and the Journal of…

Filed under:ConditionsPsoriatic ArthritisResearch Rheum Tagged with:American College of Rheumatology (ACR)Arthritis & RheumatologyguidelinePsoriatic ArthritisResearch

psoriatic arthritis hand photo

New PsA Guideline Released

Kathy Holliman  |  December 17, 2018

The ACR & the National Psoriasis Foundation (NPF) have published a joint Guideline for the Treatment of Psoriatic Arthritis (PsA). The guideline will serve as an aid to practitioners managing active PsA in patients.

Filed under:Clinical Criteria/GuidelinesConditionsPsoriatic Arthritis Tagged with:first-line use of a TNFiJoint Guideline for the Treatment of Psoriatic Arthritis (PsA)National Psoriasis Foundation (NPF)oral small molecule (OSM) drugsPsA Resource CenterPsoriatic ArthritisTNFi biologic

RISE Lifts Research: The 2018 Annual Meeting Features 6 New Studies Based on RISE Data

Susan Bernstein  |  October 3, 2018

Data from the ACR’s Rheumatology Informatics System for Effectiveness (RISE) were used by rheumatology researchers in a crop of new studies that will be presented at the 2018 ACR/ARHP Annual Meeting, Oct. 19–24 in Chicago. Six abstracts, including four oral and two poster presentations, were accepted for this year’s meeting. They explore topics ranging from…

Filed under:American College of RheumatologyEducation & TrainingProfessional Topics Tagged with:2018 ACR/ARHP Annual MeetingRheumatology Informatics System for Effectiveness (RISE) clinical data registryRISE data

Case Report: A Psoriatic Arthritis Patient with Dactylitis & Enthesitis

Samantha C. Shapiro, MD; Jemima Albayda, MD; & Ana-Maria Orbai, MD, MHS  |  September 20, 2018

A 36-year-old woman presented at the Johns Hopkins Arthritis Center for a second opinion regarding a diagnosis of psoriatic arthritis (PsA). One year prior to our evaluation, she had developed pain and stiffness in her hands, feet, knees, ankles, elbows and shoulders. She had mild plaque psoriasis of the scalp and base of the neck,…

Filed under:ConditionsOther Rheumatic ConditionsPsoriatic Arthritis Tagged with:DactylitisEnthesitisPsAPsoriatic Arthritis

4 Rheumatoid Arthritis Therapy Principles, & New Drug Info

Thomas R. Collins  |  July 19, 2018

CHICAGO—Amid what she called a “dizzying array of choices” for rheumatoid arthritis (RA)—from anti-TNF and anti-IL6-receptor therapies to B cell depletion to new biosimilar options—disease treatment should still revolve around several basic concepts, an expert said at the ACR State-of-the-Art Clinical Symposium in April. Joan Bathon, MD, chief of rheumatology at Columbia University in New…

Filed under:ConditionsRheumatoid Arthritis Tagged with:2018 State of the Art Clinical SymposiumBiosimilarsDisease-modifying antirheumatic drugs (DMARDs)ILDInterstitial Lung Disease

Study Results for 9 New Psoriatic Arthritis Drugs

Thomas R. Collins  |  June 21, 2018

CHICAGO—As Eric Ruderman, MD, professor of medicine in rheumatology at Northwestern University Feinberg School of Medicine in Chicago, began his talk on psoriatic arthritis treatment at the ACR State-of-the-Art Clinical Symposium in April, he marveled a bit at how much there was to cover. Drugs gaining prominence in the treatment of rheumatoid arthritis and dermatological…

Filed under:ConditionsDrug UpdatesOther Rheumatic Conditions Tagged with:abataceptapremilastBimekizumabguselkumabixekizumabPsoriatic ArthritisrisankizumabsecukinumabTofacitinibustekinumab

FDA Clears Pfizer’s Xeljanz for Inflammatory Bowel Disease

Reuters Staff  |  May 31, 2018

(Reuters)—The U.S. Food and Drug Administration said on Wednesday that it had approved Pfizer Inc’s drug, Xeljanz, to treat adults with moderate-to-severe active ulcerative colitis. The effectiveness of Xeljanz (tofacitinib) in treating ulcerative colitis was shown in three controlled clinical trials, including two trials that showed the drug caused disease remission in about 17-18 percent…

Filed under:Drug Updates Tagged with:Pfizer Inc.TofacitinibU.S. Food and Drug Administrationulcerative colitisXeljanz

DMARDs & Biologics Info for Rheumatology Nurses

Larry Beresford  |  March 17, 2018

SAN DIEGO—In a presentation on what rheumatology nurses should know in their daily practice about disease-modifying anti-rheumatic drugs (DMARDs) at the 2017 ACR/ARHP Annual Meeting Nov. 3–8, Jessica Farrell, PharmD, highlighted the importance of educating and counseling patients about the range of treatments and applications for rheumatologic conditions. Dr. Farrell, a clinical pharmacist at the…

Filed under:Biologics/DMARDsMeeting Reports Tagged with:ACR/ARHP Annual MeetingBiologicsDisease-modifying antirheumatic drugs (DMARDs)

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