‘Nothing but NET[osis]’: RheumMadness 2022 Anti-NET Antibodies Scouting Report

NETs haven’t been this popular since 1993 when Michael Jordan, a University of North Carolina graduate considered the best basketball player ever, popularized the phrase “nothing but NET[osis].” Just like Jordan, we’re confident our nets will entrap the other teams—including our first-round competitor, Cytokine Networks—and we will prevail.

Shruti Chandramouli, MD, is a second-year rheumatology fellow in the University of North Carolina Rheumatology Fellowship Program.

Christopher Overton, MD, is a second-year rheumatology fellow in the University of North Carolina Rheumatology Fellowship Program. 

Astia Allenzara, MD, is a first-year rheumatology fellow in the University of North Carolina Rheumatology Fellowship Program.

Michael Cunningham, MD, is a first-year rheumatology fellow in the University of North Carolina Rheumatology Fellowship Program.

Luis Palomino, MD, is a first-year rheumatology fellow in the University of North Carolina Rheumatology Fellowship Program.

References

1. Zuo Y, Yalavarthi S, Gockman K, et al. Anti-neutrophil extracellular trap antibodies and impaired neutrophil extracellular trap degradation in antiphospholipid syndrome. Arthritis Rheumatol. 2020 Dec;72(12):2130–2135.

Sources

1. Zuo Y, Yalavarthi S, Gockman K, et al. Anti-neutrophil extracellular trap antibodies and impaired neutrophil extracellular trap degradation in antiphospholipid syndrome. Arthritis Rheumatol. 2020 Dec;72(12):2130–2135.
2. de Bont CM, Stokman MEM, Faas P, et al. Autoantibodies to neutrophil extracellular traps represent a potential serological biomarker in rheumatoid arthritis. J Autoimmun. 2020 Sep;113:102484.
3. He Y, Yang FY, Sun EW. Neutrophil extracellular traps in autoimmune diseases. Chin Med J (Engl). 2018 Jul 5;131(13):1513–1519.
4. Yipp BG, Kubes P. NETosis: How vital is it? Blood. 2013 Oct 17;122(16):2784–2794.