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A Possible Diagnostic Tool: RheumMadness 2022 AI: JIA Subtypes Scouting Report

The Children’s Hospital at Montefiore Pediatric Rheumatology Fellowship Program: Alisha Akinsete, MD; Malki Peskin, MD; & Jessica Perfetto, MD  |  Issue: May 2022  |  February 14, 2022

Immunophenotyping through machine learning could be the disrupter you’ve been waiting for. This study can go all the way.


Alisha Akinsete, MD, is a third-year fellow in The Children’s Hospital at Montefiore Pediatric Rheumatology Fellowship Program, Bronx, N.Y.

 

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Malki Peskin, MD, is a second-year fellow in The Children’s Hospital at Montefiore Pediatric Rheumatology Fellowship Program, Bronx, N.Y.

Jessica Perfetto, MD, is a first-year fellow in The Children’s Hospital at Montefiore Pediatric Rheumatology Fellowship Program, Bronx, N.Y.

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References

  1. van Nieuwenhove E, Lagou V, Van Eyck L, et al. Machine learning identifies an immunological pattern associated with multiple juvenile idiopathic arthritis subtypes. Ann Rheum Dis. 2019 May;78(5):617–628.
  2. Ombrello MJ, Arthur VL, Remmers EF, et al. Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: Clinical and therapeutic implications. Ann Rheum Dis. 2017 May;76(5):906­–913.

Experience All of RheumMadness

During RheumMadness, rheumatology concepts represent teams that compete against each other in a tournament, much like basketball teams do in the NCAA’s March Madness tournament. In a series for The Rheumatologist, readers will get a chance to read the scouting reports. Check out the reports from each region:

Region: Cells

• Anti-NET Antibodies

• Cytokine Networks

• CAR-T Cells

• Pim Kinases

Region: Animal House

• Axolotl Limbs

• Dinosaur SpA

• Dalmatian Urate

• Dog Osteoarthritis

Region: Machines

• AI: JIA Subtypes

• AI: TNFi Response

• DECT in Gout

• PET in LVV

Region: People

• Reproductive Health Guide

• TNFi in Cord Blood

• Increasing +ANA

• False Positive MRI in Axial SpA

Don’t forget to submit your RheumMadness 2022 bracket by March 25. The winner of each match-up is decided by a seven-member Blue Ribbon Panel of rheumatologists. The panel will vote based on which topic they think is most important to patients, providers and researchers—both now and in the future. The more your picks match those of the panel, the more points you get. The tournament results will be released in four rounds from March 26–April 4. Prizes will be given to participants with the top scores in the following categories: 1) attending/APP, 2) fellow and 3) resident/medical student. The prize is a custom RheumMadness coffee mug and a lifetime of bragging rights.

Connect with RheumMadness by subscribing to the podcast and joining the conversation on Twitter, #RheumMadness. Learn on the RheumMadness website.

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Filed under:ConditionsResearch Rheum Tagged with:AIartificial intelligenceenthesitis-related arthritisJIAjuvenile idiopathic arthritis (JIA)RheumMadnessTechnology

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